산학협력단

연구소장 소개

안녕하십니까? 바이오소재연구소를 방문해 주셔서 감사합니다.

연구소장 한경식

• •성명 : 한경식
• •이메일 : kshan@syu.ac.kr
• •소속 : 삼육대학교 식품영양학과 교수
• •연락처 : 02-3399-1765

학력

경력 및 수상

주요 연구분야

• •동물 실험 모델 및 인체 실험을 활용한 기능성 소재의 장 미생물군집, 면역 및 뇌 건강 등에 미치는 영향 연구
• •식품, 화장품 및 동물사료에 적용 가능한 기능성 소재 개발 연구
• •다양한 생체 내외 실험 기법을 이용한 소재의 기능성 검증 및 기작 연구
• •Probiotics의 선발, 특성 규명 및 캡슐화 연구
• •인체 소화기관 생체외 모델을 이용한 다양한 식품의 소화율 평가 연구

논문

국제 전문 학술지

• •Hydrolysis by Alcalase Improves Hypoallergenic Properties of Goat Milk Protein. Korean Journal for Food Science of Animal Resources. 36, 516-522.
• •Physicochemical Characterization and Potential Prebiotic Effect of Whey Protein Isolate/Inulin Nano complex. Korean Journal for Food Science of Animal Resources. 36, 267-274.
• •In Vitro Effects of Dietary Inulin on Human Fecal Microbiota and Butyrate Production. 2015. Journal of Microbiology and Biotechnology. 25(9), 1555-1558.
• •Butyrate modulates bacterial adherence on LS174T human colorectal cells by stimulating mucin secretion and MAPK siganling pathway. 2015. Nutrition Research and Practice. 9(4), 343-349.
• •Korean ginseng modulates the ileal microbiota and mucin gene expression in the growing rat. 2014. Food and Function. 5, 1506-1512.
• •Orally administered ovine serum immunoglobulins modulate the intestinal levels of lactobacillus and enterobacteria in the growing rat. 2013. Journal of Animal Science. 91, 3724-3732.
• •Recovery of intact IgG in the gastrointestinal tract of the growing rat following ingestion of an ovine serum immunoglobulin. 2013. Journal of Animal Physiology and Animal Nutrition. 98(2), 209-214.
• •Green and gold kiwifruit peel ethanol extracts potentiate pentobarbital-induced sleep in mice via a GABAergic mechanism. 2013. Food Chemistry. 136, 160-163.
• •Comparative analysis of RNA silencing suppression activities between viral suppressors and an endogenous plant RNA-dependent RNA polymerase. 2012. Virus Genes. 44, 495-504.
• •Dietary supplementation with ovine serum immunoglobulin is associated with increased gut mucin secretion in the growing rat. 2011. Animal. 5, 1916-1922.
• •Indian culinary plants enhance glucose-induced insulin secretion and glucose consumption in INS-1 b-cells and 3T3-L1 adipocytes. 2011. Food Chemistry. 129, 1120-1125.
• •Dietary supplementation with ovine serum immunoglobulin attenuates acute effects on growth, organ weights, gut morphology and intestinal mucin production in the growing rat challenged with Salmonella enteritidis. 2011. Animal. 5, 1570-1578.
• •Ovine serum immunoglobulin has immunomodulatory effects in growing rats gavaged with Salmonella enteritidis. 2011. Journal of Nutrition. 141, 950-956.
• •Green kiwifruit modulates the colonic microbiota in growing pigs. 2011. Letters in Applied Microbiology. 52, 379-385.
• •Microencapsulation of probiotic bacteria using pH-induced gelation of sodium caseinate and gellan gum. 2011. International Dairy Journal. 21, 247-253.
• •Reproductive and metabolic endorcrinology of Romney rams selected for high or low circulating IGF-I concentrations. 2010. Small Ruminant Research. 93, 186-192.
• •Immunomodulatory effects of ovine serum immunoglobulin in the growing rat. 2010. Animal. 4, 1702-1708.
• •Rams genetically superior for IGF-1 do not exhibit improved male reproductive traits. 2009. Animal Reproduction Science. 118, 223-230.
• •The in vitro anti-pathogenic activity of immunoglobulin concentrates extracted from ovine blood. 2009. Applied Biochemisty and Biotechnology. 157, 442-452.
• •Anticancer activity of lactoferrin isolated from caprine colostrum on human cancer cell lines. 2009. International Journal of Dairy Technology. 62, 277-281.
• •Orally administered ovine serum immunoglobulins influence growth performance, organ weights and gut morphology in growing rats. 2009. Journal of Nutrition. 139, 244-249.
• •Hydrolysed casein influences intestinal mucin gene expression in the rat. 2008. Journal of Agricultural and Food Chemistry. 56, 5572-5576.
• •Characterization and purification of acidocin 1B, a bacteriocin produced by Lactobacillus acidophilus GP1B. 2007. Journal of Microbiology and Biotechnology. 17, 774-783.
• •Microencapsulation of Lactobacillus acidophilus ATCC 43121 with prebiotic substrates using a hybridization system. 2007. International Journal of Food Science and Technology. 42, 411-419.
• •Food-derived bioactive peptides influence gut function. 2007. International Journal of Sport Nutrition and Exercise Metabolism. 17, S5-S22 (Suppl).
• •Changes in the levels of insulin-like growth factors (IGF-I and IGF-II) in bovine milk according to the lactation period and parity. 2007. Asian-Aust. J. Anim. Sci. 20, 119-123.
• •Inhibitory effects of Lactobacillus acidophilus lysates on the cytotoxic activity of shiga-like toxin 2 produced from Escherichia coli O157:H7. 2006. Letters in Applied Microbiology. 43, 502-507.
• •Effects of Lactobacillus strains on cancer cell proliferation and oxidative stress in vitro. 2006. Letters in Applied Microbiology. 42, 452-458.
• •Function of cell-bound and released exopolysaccharides produced by Lactobacillus rhamnosus ATCC 9595. 2006. Journal of Microbiology and Biotechnology. 16, 939-945.
• •Rapid identification of Lactobacillus acidophilus by restriction analysis of the 16S-23S rRNA intergenic spacer region and flanking 23S rRNA gene. 2005. Biotechnology Letters. 27, 1183-1188.
• •Optimization of technical conditions for the transformation of Lactobacillus acidophilus strains by electroporation. 2005. Journal of Applied Microbiology. 99, 167-174.
• •Functionality and physico-chemical characteristics of bovine and caprine mozzarella cheeses during refrigerated storage. 2003. Journal of Dairy Science. 86, 2790-2798.
• •Bacteriocin Produced by Lactobacillus acidophilus ATCC 4356: Characterization and Purification. 2002. Food Sci. Biotechnol. 11(5), 531-536.
• •New response surface approach to optimize medium composition for production of bacteriocin by Lactobacillus acidophilus ATCC 4356. 2002. Journal of Microbiology and Biotechnology. 12, 449-456.

국내 전문 학술지

• •Estimation of digestibility of Hanwoo cuts using in vitro physicochemical gastroduodenal system. 2018. Journal of the Korean Society of Food Science and Nutrition. 47, 1029-1035.
• •Enhancement of viability of Weissella cibaria CMU by low-temperature encapsulation. 2018. Journal of Milk Science and Biotechnology. 36, 171-177.
• •Flavonoid in clover honey exerts a hypnotic effect via positive allosteric modulation of the GABAA-BZD receptor in mice. 2017. The Korean Journal of Food and Nutrition. 30, 1364-1369.
• •Development and characterization of a hydrolyzed goat milk protien/chitosan oligosaccharide nano-delivery system. 2017. Journal of Milk Science and Biotechnology. 35, 208-214.
• •The commercial value of goat milk in food industry. 2016. Korean J. Dairy Sci. Technol. 34, 173-180.
• •A study on the health status and food habits of male college students according to drinking. 2015. The Korean Journal of Food and Nutrition. 28, 73-83.
• •Study on body awareness, and health status according to body mass index of college women in Seoul area. 2015. The East Asian Society of Dietary Life. 25(1), 50-64.
• •Development of a Novel PCR Primer for Detection of Staphylococcus aureus. 2015. Journal of Agriculture and Life Sciences. 49(1), 147-153.
• •Transient expression of homologous hairpin RNA interferes with Cucumber mosaic virus infection in Nicotiana benthamiana. 2014. The Journal of the Korean Society of international Agriculture. 26(21), 1-9.
• •Adulteration of caprine milk products by bovine milk in Korea. 2013. Korean J. Dairy Sci. Technol. 31, 127-131.
• •Nutritional value and characterization of Jersey Milk. 2013. Journal of Agriculture &Life Science. 47, 111-121.
• •Use of Bacteriocin Produced by Lactococcus sp. CU216 with pH Sensitive Liposome Entrapment. 2004. Korean J. Food Sci. Ani. Resour. 24(1), 97-102.
• •Adhesion Ability and Inhibition of Lactobacillus acidophilus on Adhesion of Enterohemorrhagic E. coli O157:H7 to Intestinal Epithelial Cells. 2004. Korean J. Food Sci. Ani. Resour. 24(1), 86-91.
• •Purification, Bacteriolytic Action and Plasmid Isolation of Acidocin 4A Produced by Lactobacillus acidophilus GP4A. 2003. J. Korean Dairy Technol. Sci. 21(2), 114-119.
• •Formation of Cheese Flavor and EMC Technology. 2003. J. Korean Dairy Technol. Sci. 21(2), 88-96.
• •Dry Enteric Coating Process of Lactic Acid Bacteria by Hybridization System. 2002. Korean J. Food Sci. Technol. 34(5), 856-861.
• •Antimicrobial Effects of a Bacteriocin Mixture from Lactic Acid Bacteria against Foodborne Pathogens. 2002. Korean J. Food Sci. Ani. Resour. 22(2), 164-171.
• •Development of Bacteriocin Preparation from Lactic Acid Bacteria against Salmonella Using an Experimental Design for Mixtures. 2002. J. Korean Dairy Technol. Sci. 20(1), 1-8.
• •Characterization and Inhibitory Activity on Staphylococcus aureus of a Bacteriocin Produced by Lactobacillus plantarum KU107. 2002. Korean J. Food Ani. Resour. 22(1), 81-86.
• •Estimation of Insulin Like Growth Factor-I (IGF-I) Concentration in Raw Milk and Milk Whey by Various Milk Heat Treatment. 2001. J. Korean. Dairy Technol. Sci. 19(2), 98-102.
• •A Study on the Dairy Information System and Effective Dairy Extension Service System. 2001. J. Korean. Dairy Technol. Sci. 19(1), 22-29.
• •Fractionation and Physicochemical Characteristics of Caprine Casein by DEAE-Cellulose. 2000. J. Korean. Dairy Technol. Sci. 18(1), 1-8.
• •Characteristics and Purification of Bacteriocin Produced by Lactobacillus acidophilus GP4A. 1999. J. Korean. Dairy Technol. Sci. 17(1), 1-10.
• •Electrophoretic Analysis of Heated Milk Fat Globule Membrane Protein. 1997. Korean J. Food Sci. Ani. Resour. 17(3), 240-245.
• •Molecular Composition and Fractionation of Colostral Casein with Advancing Lactation. 1997. Korean J Dairy Sci. 19(1), 49-58.