산학협력단

생체이용률조절연구소

연구소장 소개

학력

• •강원대학교 약학대학 졸업; 약학박사
• •삼육대학교 약학대학 졸업; 약학석사
• •삼육대학교 약학대학 졸업; 약학사

경력

• •2015. 09 ~ 현재: 생체이용률조절연구소장
• •2015. 03 ~ 현재: 삼육대학교 약학대학; 조교수
• •2015. 03 ~ 현재: (사) 대한약학회 정회원
• •2015. 03 ~ 현재: (사) 한국약제학회 정회원
• •2013. 04 ~ 2015. 02: The University of Mississippi, School of Pharmacy, Pharmaceutics Department; 박사후 연구원
• •2004. 05 ~ 2008. 02: (주) 한독약품 중앙연구소; Project Leader
• •2001. 02 ~ 2004. 04: 초당약품 (주) 중앙연구소; 선임연구원

주요연구분야

• 1 고온용융압출기술(Hot Melt Extrusion Technology)을 이용한 제제화
• 2 난용성 약물의 가용화 기술
• 3 제제화를 위한 다양한 첨가제류의 처방 및 조성물 확립 기술
• 4 위장관 투과 속도 및 양의 조절 연구 기술

논문, 책 특허

논문 (2015~)

• • Chulhun Park, Nileshkumar M. Meghani, Yongkwan Shin, Euichaul Oh, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Thao Truong-Dinh Tran, Phuong Ha-Lien Tran and Beom-Jin Lee, Investigation of Crystallization and Salt Formation of Poorly Water-Soluble Telmisartan for Enhanced Solubility, Pharmaceutics, 2019, 11, 102-117
• • Kyu-Yeol Nama, Sang Min Cho, Youn-Woong Choi, Chulhun Park, Nileshkumar M. Meghani, Jun-Bom Park, Beom-Jin Lee, Double controlled release of highly insoluble cilostazol using surfactant- driven pH dependent and pH-independent polymeric blends and in vivo bioavailability in beagle dogs, International Journal of Pharmaceutics, 2019, 558, 284-290
• • Changmin Kang, Ju-Hyun Lee, Dong-Wook Kim, Beom-Jin Lee, and Jun-Bom Park, Preparation of Sustained Release Tablet with Minimized Usage of Glyceryl Behenate Using Post-Heating Method, AAPS PharmSciTech, 2018, 19(7), 3067-3075
• • Seung Jin Ko, Ju-Hyun Lee, Chin-Yang Kang, Jun-Bom Park, Granulation development in batch-to-batch and continuous processes from a quality by design perspective, Journal of Drug Delivery Science and Technology, 2018, 46, 34-45
• • Jun-Bom Park, Chulhun Park, Zhong Zhu Piao, Hardik H. Amin, Nilesh M. Meghani, Phuong H.L. Tran, Thao T.D. Tran, Jing-Hao Cui, Qing-Ri Cao, Euichaul Oh, Beom-Jin Lee, pH-independent controlled release tablets containing nanonizing valsartan solid dispersions for less variable bioavailability in humans, Journal of Drug Delivery Science and Technology, 2018, 46, 365-377.
• • Nilesh M. Meghani, Hardik H. Amin, Chulhun Park, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee, Design and evaluation of clickable gelatin-oleic nanoparticles using fattigation-platform for cancer therapy, International Journal of Pharmaceutics, 2018, 545, 101-112.
• • Kyung-Ho Lee · Chulhun Park · Giwon Oh · Jun-Bom Park · Beom-Jin Lee, New blends of hydroxypropylmethylcellulose and Gelucire 44/14: physical property and controlled release of drugs with different solubility, Journal of Pharmaceutical Investigation, 2018, 48, 313-321.
• • Namhyun Baek, Ga-Hui Oh, Chulhun Park, Thuy Thi Thanh Tran, Young Joon Park, Euichaul Oh, Hau Le, Thao T.D. Tran, Jun-Bom Park, Beom-Jin Lee, Reprecipitation of poorly water-soluble cilostazol crystals using adsorbing carriers for enhanced dissolution and physicochemical modification. Journal of Drug Delivery Science and Technology, 2018, 43, 477-486.
• • Sung-min Choi, Chin-Yang Kang, Beom Jin Lee and Jun-Bom Park, In Vitro-In Vivo Correlation Using In Silico Modeling of Physiological Properties, Metabolites, and Intestinal Metabolism. Current Drug Metabolism, 2017, 18(11), 973-982.
• • Sultan Alshehri, Roshan Tiwari, Bader Alsulays, Eman Ashour, Abdullah Alshetaili, Bjad Almutairy, Jun-Bom Park, Joseph Morott, Bhupinder Sandhu, Soumyajit Majumdar & Michael A. Repkae, Investigation of the combined effect of MgO and PEG on the release profile of mefenamic acid prepared via hot-melt extrusion techniques. Pharmaceutical Development and Technology, 2017, 22(6), 740-753.
• • Daoqi Luo, Joo Hee Kim, Chulhun Park, Euichaul Oh, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee, Design of fixed dose combination and physicochemical characterization of enteric-coated bilayer tablet with circadian rhythmic variations containing telmisartan and pravastatin sodium. International Journal of Pharmaceutics, 2017, 523, 343-356.
• • Ilhwan Hwang, Chin-Yang Kang, Jun-Bom Park, Advances in hot-melt extrusion technology toward pharmaceutical objectives. Journal of Pharmaceutical Investigation, 2017, 47, 123-132.
• • Jun-Bom Park, Dong-Wook Kim, Sung-Hoon Lee, Kwon-Yeon Weon, Development of a Process Analytical Technology(PAT) method using near-infrared spectroscopy system for evaluating an active coating process for a low-dose drug. Journal of Drug Delivery Science and Technology, 2017, 39, 8-15.
• • Jun-Bom Park, Beom-Jin Lee, Chin-Yang Kang, Roshan V. Tiwari, Michael A. Repka, Process analytical quality control of tailored drug release formulation prepared via hot-melt extrusion technology. Journal of Drug Delivery Science and Technology, 2017, 38, 51-58.
• • Bader B. Alsulays, Vijay Kulkarni, Sultan M. Alshehri, Bjad K. Almutairy, Eman A. Ashour, Joseph T. Morott, Abdullah S. Alshetaili, Jun-Bom Park, Roshan V. Tiwari & Michael A. Repka, Preparation and evaluation of enteric coated tablets of hot melt extruded lansoprazole. Drug Development and Industrial Pharmacy, 2017, 43(5), 789-796.
• • Abdullah S. Alshetaili, Bjad K. Almutairy, Roshan V. Tiwari, Joseph T. Morott, Sultan M. Alshehri, Xin Feng, Bader B. Alsulays, Jun-Bom Park, Feng Zhang and Michael A Repka, Preparation and Evaluation of Hot-Melt Extruded Patient-Centric Ketoprofen Mini-tablets. Current Drug Delivery, 2016, 13(5), 730-741.
• • Eman A. Ashour, Vijay Kulkarni, Bjad Almutairy, Jun-Bom Park, Sejal Shah, Soumyajit Majumdar, Michael A. Repka, Influence of Pressurized Carbon Dioxide on Ketoprofen-Incorporated Hot-Melt Extruded Low Molecular Weight Hydroxypropylcellulose. Drug Development and Industrial Pharmacy, 2016, 42 (1), 123-130.
• • Jun-Bom Park, Byoung-Kyu Choi, Chin-Yang Kang, Effects of absorbent materials on a self-emulsifying drug delivery system for a poorly water soluble drug. Journal of Pharmaceutical Investigation, 2015, 45(6), 529-539.
• • Dong-Wook Kim, Jun-Bom Park, Development and Pharmaceutical Approach for Sustained-Released Metformin Succinate Tablets. Journal of Drug Delivery Science and Technology, 2015, 30, 90-99.
• • Jae Eun Park, Do Kyung Lee, Kyung Tae Kim, Jae Goo Seo, Myung Jun Chung, Nam Joo Ha, Jun-Bom Park & Kyungjae Kim, Hepatoprotective effects of dual-coated and uncoated mixture of probiotics in rats. Biotechnology & Biotechnological Equipment, 2015, 29 (6), 1164-1168.
• • Bader B. Alsulays, Jun-Bom Park, Sultan M. Alshehri, Joseph T. Morott, Saad M. Alshahrani, Roshan V. Tiwari, Abdullah S. Alshetaili, Soumyajit Majumdar, Nigel Langley, Karl Kolter, Andreas Gryczke, Michael A. Repka, Influence of molecular weight of carriers and processing parameters on the extrudability, drug release, and stability of fenofibrate formulations processed by hot-melt extrusion. Journal of Drug Delivery Science and Technology, 2015, 29, 189-198.
• • Manjeet. B. Pimparade, Joseph T. Morott, Jun-Bom Park, Vijay I. Kulkarni, Soumyajit Majumdar, Zhuoyang Lian, Elanor Pinto, Vivian Bi, Thomas Durig, Michael A. Repka, Taste Masked Formulations Using Hot-Melt Extrusion Technology with Modified Screw Configuration and Pore Forming Agents. International journal of pharmaceutics, 2015, 487, 167-176.
• • Sultan Alshehri, Jun-Bom Park, Bader Alsulays, Bjad Almutairy, Abdullah Alshetaili, Joe Morott, Sejal Shah, Vijay Kulkarni, Soumyajit Majumdar, Scott Martin, Sanjay Mishra, Lijia Wang, Michael Repka, Solubility Enhancement and Taste Masked effect via Molecular Interaction on Hot Melt Extrudates and the Orally Disintegrating Tablets. Journal of Drug Delivery Science and Technology, 2015, 27, 18-27.
• • Saad Alshahrani, Wenli Lu, Jun-Bom Park, Joseph Morott, Bader Alsulays, Soumyajit Majumdar, Nigel Langley, Karl Kolter, Andreas Gryczke, Michael Repka, Stability Enhanced Hot Melt Extruded Amorphous Solid Dispersions via Combinations of Soluplus® and HPMCAS-HF. AAPS Pharmsitech, 2015, 16, 824-834.
• • Joe Morott, Manjeet Pimparade, Jun-Bom Park Soumyajit Majumdar, Z. Lian, E. Pinto, V. Bi, Tom. Durig, Michael A. Repka, The Effects of Screw Configuration and Polymeric Carriers on Hot-Melt Extruded Taste-Masked Formulations Incorporated into Orally Disintegrating Tablets. Journal of pharmaceutical science, 2015, 104, 124-134.
• • Xin Feng, Xingyou Ye, Jun-Bom Park, Wenli Lu, Joe Morrot, Vivian Bi, Michael A. Repka, Evaluation of the recrystallization kinetics of hot melt extruded polymeric solid dispersions using an improved Avrami equation. Drug Development and Industrial Pharmacy, 2015, 41, 1479-1487.
• • Jun-Bom Park, Young-Joon Park, Chin-Yang Kang and Beom-Jin Lee, Modulation of microenvironmental pH and utilization of alkalizers in crystalline solid dispersion for enhanced solubility and stability of clarithromicin. Archives of Pharmacal Research, 2015, 38, 839-848.
• • Jun-Bom Park, Suneela Prodduturi, Vijay I. Kulkarni, Melissa R. Jacob, Shabana I. Khan, Steven P. Stodghill, Michael A. Repka, Development of an antifungal denture adhesive film for oral candidiasis utilizing hot melt extrusion technology. Expert Opinion on Drug Delivery, 2015, 12, 1-13.

책

• • Jun-Bom Park and Beom-jin Lee, Emerging oral controlled-release technology for optimal therapy. Future Science, 2013, Nov. 40-53.
• • 이범진, 전인구, 한효경, 박준범, 임지성, 염류의약품 물성과 선택 및 응용. 신일북스 (역자). 2013.

특허

• • Hemlata Patil, Vijay Kulkarni, Jun-Bom Park, Soumyajit Majumdar, Michael A. Repka, Systems and Methods for Preparing Lipid Nanoparticles.2014 # USSN 61/969,444
• • 박준범, 최성민, 생리학적 체내 동태 연구 모델링을 이용한 약제학적 조성물의 제조 방법, 2018, 출원중 2018.07.10
• • 박준범, 강창민, 친수성 약물을 포함하는 서방성 제제의 제조 방법, 2018, 제 10-1881749 호.
• • 박준범, 강진양, 반복 고온용융 압출 성형된 약제학적 조성물의 제조 방법 및 이에 의해 제조된 약제학적 조성물, 2017, 제 10-1801476 호.
• • 박준범, 이범진, 고온용융 압출을 이용한 저함량 약제학적 조성물의 제조방법, 2013, 제 10-1390946 호.